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SUPT5H anticorps (AA 125-425)

SUPT5H Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6148739
  • Antigène Voir toutes SUPT5H Anticorps
    SUPT5H (Transcription Elongation Factor SPT5 (SUPT5H))
    Épitope
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 125-425
    Reactivité
    • 32
    • 11
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 30
    • 2
    Lapin
    Clonalité
    • 27
    • 5
    Polyclonal
    Conjugué
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp SUPT5H est non-conjugé
    Application
    • 28
    • 16
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    LQNLWRDQRE EELGEYYMKK YAKSSVGETV YGGSDELSDD ITQQQLLPGV KDPNLWTVKC KIGEERATAI SLMRKFIAYQ FTDTPLQIKS VVAPEHVKGY IYVEAYKQTH VKQAIEGVGN LRLGYWNQQM VPIKEMTDVL KVVKEVANLK PKSWVRLKRG IYKDDIAQVD YVEPSQNTIS LKMIPRIDYD RIKARMSLKD WFAKRKKFKR PPQRLFDAEK IRSLGGDVAS DGDFLIFEGN RYSRKGFLFK SFAMSAVITE GVKPTLSELE KFEDQPEGID LEVVTESTGK EREHNFQPGD N
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 125-425 of human SUPT5H/SPT5 (NP_003160.2).
    Isotype
    IgG
    Top Product
    Discover our top product SUPT5H Anticorps primaire
  • Indications d'application
    WB,1:200 - 1:2000
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    SUPT5H (Transcription Elongation Factor SPT5 (SUPT5H))
    Autre désignation
    SUPT5H (SUPT5H Produits)
    Synonymes
    anticorps SPT5, anticorps SPT5H, anticorps Tat-CT1, anticorps F13P17.5, anticorps F13P17_5, anticorps Spt5, anticorps etID10129.15, anticorps etID37101.15, anticorps fb37g01, anticorps fb95e05, anticorps fog, anticorps foggy, anticorps wu:fb37g01, anticorps wu:fb95e05, anticorps wu:fc10f02, anticorps spt5, anticorps spt5h, anticorps tat-ct1, anticorps CG7626, anticorps DSIF, anticorps Dmel\\CG7626, anticorps Dspt5, anticorps dDSIF, anticorps dSpt5, anticorps CaO19.1453, anticorps SPT5 homolog, DSIF elongation factor subunit, anticorps transcription elongation factor SPT5, anticorps Transcription elongation factor Spt5, anticorps transcription elongation factor Spt5, anticorps transcription elongation factor spt5, anticorps hypothetical protein, anticorps SPT5 homolog, DSIF elongation factor subunit S homeolog, anticorps CG7626 gene product from transcript CG7626-RA, anticorps Transcription elongation factor SPT5, anticorps transcription elongation factor, anticorps SUPT5H, anticorps LOC413814, anticorps AT2G34210, anticorps spt5, anticorps MGYG_08422, anticorps TERG_05483, anticorps PGTG_18458, anticorps supt5h, anticorps Supt5h, anticorps supt5h.S, anticorps Spt5, anticorps spt-5, anticorps SPT5
    Sujet
    Component of the DRB sensitivity-inducing factor complex (DSIF complex, which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme. Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites. DSIF can also positively regulate transcriptional elongation and is required for the efficient activation of transcriptional elongation by the HIV-1 nuclear transcriptional activator, Tat. DSIF acts to suppress transcriptional pausing in transcripts derived from the HIV-1 LTR and blocks premature release of HIV-1 transcripts at terminator sequences.,SUPT5H,SPT5,SPT5H,Tat-CT1,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,SUPT5H
    Poids moléculaire
    120 kDa/121 kDa
    ID gène
    6829
    UniProt
    O00267
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