SUPV3L1 anticorps (AA 577-786)

N° du produit ABIN6148741

Détail du produit anti-SUPV3L1 anticorps

Antigène: SUPV3L1 (Suppressor of Var1, 3-Like 1 (SUPV3L1))

Épitope: AA 577-786

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUPV3L1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Séquence: APINKKQPFV CSSLLQFARQ YSRNEPLTFA WLRRYIKWPL LPPKNIKDLM DLEAVHDVLD LYLWLSYRFM DMFPDASLIR DLQKELDGII QDGVHNITKL IKMSETHKLL NLEGFPSGSQ SRLSGTLKSQ ARRTRGTKAL GSKATEPPSP DAGELSLASR LVQQGLLTPD MLKQLEKEWM TQQTEHNKEK TESGTHPKGT RRKKKEPDSD

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 577-786 of human SUPV3L1 (NP_003162.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:4000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SUPV3L1

Antigène: SUPV3L1 (Suppressor of Var1, 3-Like 1 (SUPV3L1))

Autre désignation: SUPV3L1 (SUPV3L1 Produits)

Synonymes: anticorps SUV3, anticorps 6330443E10Rik, anticorps wu:fc19b02, anticorps wu:fe37e06, anticorps Suv3 like RNA helicase, anticorps suppressor of var1, 3-like 1 (S. cerevisiae), anticorps SUV3-like helicase, anticorps SUPV3L1, anticorps Supv3l1, anticorps supv3l1

Sujet: Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA and tRNA-like molecules. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria, regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.,SUPV3L1,SUV3,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,SUPV3L1

Poids moléculaire: 87 kDa

ID gène: 6832

UniProt: Q8IYB8