Nesprin3 anticorps (AA 740-920)

N° du produit ABIN6148766

Détail du produit anti-Nesprin3 anticorps

Antigène: Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

Épitope: AA 740-920

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nesprin3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: LRLLEESLLS LIRNWHLQRM EVDSGKKMVF TNNIPKSGFL INPMDPIPRH RRRANLLQEE EGSHEDFSQL LRNFGQWLQV ENSKLVRIIA MRTSTAEDLR TRKSKLQELE ARVPEGQHLF ENLLRLGPAR GTSDELEDLR YQWMLYKSKL KDSGHLLTQS SPGEPTGFQK TRRWRGLGSL F

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 740-920 of human SYNE3 (NP_689805.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Nesprin3

Antigène: Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

Autre désignation: SYNE3 (C14orf49 Produits)

Sujet: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.,SYNE3,C14orf139,C14orf49,KASH3,LINC00341,NCRNA00341,NET53,Nesp3,nesprin-3,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,SYNE3

Poids moléculaire: 68 kDa/111 kDa/112 kDa

ID gène: 161176

UniProt: Q6ZMZ3

Pathways: Maintenance of Protein Location