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TAB1 anticorps (AA 205-504)

TAB1 Reactivité: Humain WB, IF, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6148795
  • Antigène Voir toutes TAB1 Anticorps
    TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
    Épitope
    • 15
    • 15
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 205-504
    Reactivité
    • 93
    • 41
    • 28
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 97
    • 9
    • 2
    Lapin
    Clonalité
    • 100
    • 8
    Polyclonal
    Conjugué
    • 41
    • 9
    • 7
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp TAB1 est non-conjugé
    Application
    • 69
    • 48
    • 26
    • 26
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    Séquence
    VDHTTENEDE LFRLSQLGLD AGKIKQVGII CGQESTRRIG DYKVKYGYTD IDLLSAAKSK PIIAEPEIHG AQPLDGVTGF LVLMSEGLYK ALEAAHGPGQ ANQEIAAMID TEFAKQTSLD AVAQAVVDRV KRIHSDTFAS GGERARFCPR HEDMTLLVRN FGYPLGEMSQ PTPSPAPAAG GRVYPVSVPY SSAQSTSKTS VTLSLVMPSQ GQMVNGAHSA STLDEATPTL TNQSPTLTLQ STNTHTQSSS SSSDGGLFRS RPAHSLPPGE DGRVEPYVDF AEFYRLWSVD HGEQSVVTAP
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 205-504 of human TAB1 (NP_006107.1).
    Isotype
    IgG
    Top Product
    Discover our top product TAB1 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:10 - 1:100,IP,1:50 - 1:200
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
    Autre désignation
    TAB1 (TAB1 Produits)
    Synonymes
    anticorps 3'-Tab1, anticorps MAP3K7IP1, anticorps 2310012M03Rik, anticorps Map3k7ip1, anticorps b2b449Clo, anticorps TGF-beta activated kinase 1 (MAP3K7) binding protein 1, anticorps TGF-beta activated kinase 1/MAP3K7 binding protein 1, anticorps TAB1, anticorps Tab1
    Sujet
    The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported.,TAB1,3'-Tab1,MAP3K7IP1,Signal Transduction,Kinase,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,TAB1
    Poids moléculaire
    49 kDa/54 kDa
    ID gène
    10454
    UniProt
    Q15750
    Pathways
    Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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