TLE1 anticorps (AA 256-355)

N° du produit ABIN6149204

Détail du produit anti-TLE1 anticorps

Antigène: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Épitope: AA 256-355

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLE1 est non-conjugé

Application: Western Blotting (WB)

Séquence: DPSSPRASPA HSPRENGIDK NRLLKKDASS SPASTASSAS STSLKSKEMS LHEKASTPVL KSSTPTPRSD MPTPGTSATP GLRPGLGKPP AIDPLVNQAA

Réactivité croisée: Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 256-355 of human TLE1 (NP_005068.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TLE1

Antigène: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Autre désignation: TLE1 (TLE1 Produits)

Synonymes: anticorps ESG, anticorps ESG1, anticorps GRG1, anticorps C230057C06Rik, anticorps Estm14, anticorps Grg1, anticorps Tle4l, anticorps TLE1, anticorps transducin like enhancer of split 1, anticorps transducin-like enhancer protein 1, anticorps transducin-like enhancer of split 1, anticorps transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila), anticorps TLE1, anticorps Smp_150080, anticorps Tle1, anticorps LOC100354911, anticorps LOC100524475, anticorps LOC100061341

Sujet: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression (By similarity. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.,TLE1,ESG,ESG1,GRG1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Wnt/β-Catenin Signaling Pathway,Stem Cells,TLE1

Poids moléculaire: 83 kDa

ID gène: 7088

UniProt: Q04724

Pathways: Signalisation WNT, SARS-CoV-2 Protein Interactome