UGT1A4 anticorps (AA 29-150)

N° du produit ABIN6149897

Détail du produit anti-UGT1A4 anticorps

Antigène: UGT1A4 (UDP Glucuronosyltransferase 1 Family, Polypeptide A4 (UGT1A4))

Épitope: AA 29-150

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UGT1A4 est non-conjugé

Application: Western Blotting (WB)

Séquence: GKVLVVPTDG SPWLSMREAL RELHARGHQA VVLTPEVNMH IKEEKFFTLT AYAVPWTQKE FDRVTLGYTQ GFFETEHLLK RYSRSMAIMN NVSLALHRCC VELLHNEALI RHLNATSFDV VL

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 29-150 of human UGT1A4 (NP_009051.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur UGT1A4

Antigène: UGT1A4 (UDP Glucuronosyltransferase 1 Family, Polypeptide A4 (UGT1A4))

Autre désignation: UGT1A4 (UGT1A4 Produits)

Synonymes: anticorps HUG-BR2, anticorps UDPGT, anticorps UDPGT 1-4, anticorps UGT-1D, anticorps UGT1-04, anticorps UGT1.4, anticorps UGT1D, anticorps UGT1, anticorps UGT1A4, anticorps UDP glucuronosyltransferase family 1 member A4, anticorps UDP-glucuronosyltransferase 1-4, anticorps UGT1A4, anticorps UGT1-4

Sujet: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.,UGT1A4,HUG-BR2,UDPGT,UDPGT 1-4,UGT-1D,UGT1-04,UGT1.4,UGT1A4S,UGT1D,UDPGT1-4,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Drug metabolism,UGT1A4

Poids moléculaire: 49 kDa/60 kDa

ID gène: 54657

UniProt: P22310

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha