UQCRFS1 anticorps (AA 79-274)

N° du produit ABIN6149963

Détail du produit anti-UQCRFS1 anticorps

Antigène: UQCRFS1 (Ubiquinol-Cytochrome C Reductase, Rieske Iron-Sulfur Polypeptide 1 (UQCRFS1))

Épitope: AA 79-274

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UQCRFS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: SHTDIKVPDF SEYRRLEVLD STKSSRESSE ARKGFSYLVT GVTTVGVAYA AKNAVTQFVS SMSASADVLA LAKIEIKLSD IPEGKNMAFK WRGKPLFVRH RTQKEIEQEA AVELSQLRDP QHDLDRVKKP EWVILIGVCT HLGCVPIANA GDFGGYYCPC HGSHYDASGR IRLGPAPLNL EVPTYEFTSD DMVIVG

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 79-274 of human UQCRFS1 (NP_005994.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-UQCRFS1 (ABIN6149963)

Hu, Nie, Chen, Xie, Fan, Wang, Long, Yan, Zhong, Yan: "Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells." dans: The international journal of biochemistry & cell biology, Vol. 89, pp. 42-56, (2017) (PubMed).

Détails sur UQCRFS1

Antigène: UQCRFS1 (Ubiquinol-Cytochrome C Reductase, Rieske Iron-Sulfur Polypeptide 1 (UQCRFS1))

Autre désignation: UQCRFS1 (UQCRFS1 Produits)

Synonymes: anticorps uqcrfs1, anticorps MGC53134, anticorps rip1, anticorps ris1, anticorps risp, anticorps uqcr5, anticorps fb78f10, anticorps wu:fb05d11, anticorps wu:fb78f10, anticorps wu:fj05e12, anticorps zgc:73109, anticorps zgc:85614, anticorps GLEAN_00043, anticorps RIP1, anticorps RIS1, anticorps RISP, anticorps UQCR5, anticorps 4430402G14Rik, anticorps AI875505, anticorps LRRGT00195, anticorps UQCRFSL1, anticorps ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 S homeolog, anticorps ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1, anticorps cytochrome b-c1 complex subunit Rieske, mitochondrial, anticorps iron-sulfur protein 1, anticorps uqcrfs1.S, anticorps uqcrfs1, anticorps LOC661125, anticorps LOC705178, anticorps UQCRFS1, anticorps Uqcrfs1, anticorps LOC100227575, anticorps isp1

Sujet: [Cytochrome b-c1 complex subunit Rieske, mitochondrial]: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII, ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII and cytochrome c oxidase (complex IV, CIV, that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. The Rieske protein is a catalytic core subunit containing a [2Fe-2S] iron-sulfur cluster. It cycles between 2 conformational states during catalysis to transfer electrons from the quinol bound in the Q(0 site in cytochrome b to cytochrome c1 (By similarity. Incorporation of UQCRFS1 is the penultimate step in complex III assembly.,UQCRFS1,RIP1,RIS1,RISP,UQCR5,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,UQCRFS1

Poids moléculaire: 29 kDa

ID gène: 7386

UniProt: P47985

Pathways: Proton Transport