Plakophilin 1 anticorps (N-Term) (CF®647)

N° du produit ABIN6166951

Détail du produit anti-Plakophilin 1 anticorps (CF®647)

Antigène: Plakophilin 1 (PKP1)

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Plakophilin 1 est conjugé à/à la CF®647

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Fonction: Mouse Monoclonal anti-Plakophilin-1 (10B2), CF647 Conjugate

Attributs du produit: This antibody recognizes a protein of 75 kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: N-terminus of human Plakophilin-1 protein (exact sequence is proprietary)

Clone: 10B2

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry 0.5-1 μg/million cells/0.1 mL

• Immunofluorescence 1-2 μg/mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

HaCat Cells.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur Plakophilin 1

Antigène: Plakophilin 1 (PKP1)

Autre désignation: Plakophilin-1 (PKP1 Produits)

Synonymes: anticorps PKP1, anticorps fb30d08, anticorps wu:fb30d08, anticorps AI528551, anticorps B6P, anticorps plakophilin 1, anticorps plakophilin 1b, anticorps PKP1, anticorps pkp1b, anticorps Pkp1

Sujet: B6P, B, 6 protein, PKP1, Plakophilin-1 (ectodermal dysplasia/skin fragility syndrome)

Poids moléculaire: 75 kDa

ID gène: 5317, 497350

UniProt: Q13835