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IFI27 anticorps (AA 1-100)

IFI27 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6218449
  • Antigène Voir toutes IFI27 Anticorps
    IFI27 (Interferon, alpha-Inducible Protein 27 (IFI27))
    Épitope
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-100
    Reactivité
    • 33
    • 6
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 31
    • 2
    Lapin
    Clonalité
    • 32
    • 1
    Polyclonal
    Conjugué
    • 15
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IFI27 est non-conjugé
    Application
    • 17
    • 13
    • 13
    • 13
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Séquence
    MEASALTSSA VTSVAKVVRV ASGSAVVLPL ARIATVVIGG VVAVPMVLSA MGFTAAGIAS SSIAAKMMSA AAIANGGGVA SGSLVATLQS LGATGLSGLT
     Réactivité croisée
    Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IFI27 (NP_005523.3).
    Isotype
    IgG
    Top Product
    Discover our top product IFI27 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    IFI27 (Interferon, alpha-Inducible Protein 27 (IFI27))
    Autre désignation
    IFI27 (IFI27 Produits)
    Synonymes
    anticorps FAM14D, anticorps ISG12, anticorps ISG12A, anticorps P27, anticorps IRG1, anticorps Ifi27l, anticorps Ifi27l1, anticorps isg12(a), anticorps interferon alpha inducible protein 27, anticorps interferon, alpha-inducible protein 27, anticorps IFI27, anticorps Ifi27
    Sujet
    Probable adapter protein involved in different biological processes. Part of the signaling pathways that lead to apoptosis. Involved in type-I interferon-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9. Also functions in TNFSF10-induced apoptosis. May also have a function in the nucleus, where it may be involved in the interferon-induced negative regulation of the transcriptional activity of NR4A1, NR4A2 and NR4A3 through the enhancement of XPO1-mediated nuclear export of these nuclear receptors. May thereby play a role in the vascular response to injury (By similarity. In the innate immune response, has an antiviral activity towards hepatitis C virus/HCV. May prevent the replication of the virus by recruiting both the hepatitis C virus non-structural protein 5A/NS5A and the ubiquitination machinery via SKP2, promoting the ubiquitin-mediated proteasomal degradation of NS5A.,IFI27,FAM14D,ISG12,ISG12A,P27,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,IFI27
    Poids moléculaire
    11 kDa
    ID gène
    3429
    UniProt
    P40305
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy
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