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NR1H3 anticorps (AA 50-330)

NR1H3 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6219352
  • Antigène Voir toutes NR1H3 Anticorps
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    Épitope
    • 16
    • 15
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-330
    Reactivité
    • 77
    • 56
    • 45
    • 17
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 85
    • 9
    • 2
    Lapin
    Clonalité
    • 78
    • 18
    Polyclonal
    Conjugué
    • 44
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp NR1H3 est non-conjugé
    Application
    • 82
    • 31
    • 27
    • 27
    • 27
    • 10
    • 10
    • 8
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    AGGTAGVGLE AAEPTALLTR AEPPSEPTEI RPQKRKKGPA PKMLGNELCS VCGDKASGFH YNVLSCEGCK GFFRRSVIKG AHYICHSGGH CPMDTYMRRK CQECRLRKCR QAGMREECVL SEEQIRLKKL KRQEEEQAHA TSLPPRASSP PQILPQLSPE QLGMIEKLVA AQQQCNRRSF SDRLRVTPWP MAPDPHSREA RQQRFAHFTE LAIVSVQEIV DFAKQLPGFL QLSREDQIAL LKTSAIEVML LETSRRYNPG SESITFLKDF SYNREDFAKA G
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 50-330 of human LXRalpha (NP_005684.2).
    Isotype
    IgG
    Top Product
    Discover our top product NR1H3 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze / thaw cycles
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Qian, Ma, Wu, Yu, Lin, Ying, Wen, Gao: "G004, a synthetic sulfonylurea compound, exerts anti-atherosclerosis effects by targeting SIRT1 in ApoE-/- mice." dans: Vascular pharmacology, Vol. 89, pp. 49-57, (2017) (PubMed).

  • Antigène
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    Autre désignation
    NR1H3 (NR1H3 Produits)
    Synonymes
    anticorps NR1H3, anticorps LXR-a, anticorps LXRA, anticorps RLD-1, anticorps AU018371, anticorps LXR, anticorps RLD1, anticorps Unr1, anticorps LXRalpha, anticorps LXR-alpha, anticorps im:7141239, anticorps wu:fd59b01, anticorps zgc:113339, anticorps zgc:158542, anticorps nuclear receptor subfamily 1 group H member 3, anticorps nuclear receptor subfamily 1, group H, member 3, anticorps NR1H3, anticorps nr1h3, anticorps Nr1h3
    Sujet
    The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,NR1H3,LXR-a,LXRA,RLD-1,LXR alpha,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Lipids,NR1H3
    Poids moléculaire
    43 kDa/45 kDa/50 kDa
    ID gène
    10062
    UniProt
    Q13133
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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