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TEK anticorps (AA 500-750)

TEK Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6223056
  • Antigène Voir toutes TEK Anticorps
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Épitope
    • 20
    • 19
    • 16
    • 11
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 500-750
    Reactivité
    • 145
    • 75
    • 49
    • 22
    • 4
    • 3
    Humain
    Hôte
    • 128
    • 26
    • 6
    • 3
    • 2
    Lapin
    Clonalité
    • 134
    • 31
    Polyclonal
    Conjugué
    • 72
    • 12
    • 9
    • 8
    • 8
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TEK est non-conjugé
    Application
    • 82
    • 60
    • 40
    • 40
    • 38
    • 33
    • 14
    • 13
    • 13
    • 8
    • 8
    • 8
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    EIVTLNYLEP RTEYELCVQL VRRGEGGEGH PGPVRRFTTA SIGLPPPRGL NLLPKSQTTL NLTWQPIFPS SEDDFYVEVE RRSVQKSDQQ NIKVPGNLTS VLLNNLHPRE QYVVRARVNT KAQGEWSEDL TAWTLSDILP PQPENIKISN ITHSSAVISW TILDGYSISS ITIRYKVQGK NEDQHVDVKI KNATITQYQL KGLEPETAYQ VDIFAENNIG SSNPAFSHEL VTLPESQAPA DLGGGKMLLI A
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 500-750 of human TEK (NP_000450.2).
    Isotype
    IgG
    Top Product
    Discover our top product TEK Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:100
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Huang, Han, Sun, Zhao, Liu, Yuan, Mao, Peng, Liu, Yin, He: "Kv1.3 channel blocker (ImKTx88) maintains blood-brain barrier in experimental autoimmune encephalomyelitis." dans: Cell & bioscience, Vol. 7, pp. 31, (2017) (PubMed).

    Chen, Ren, Zhang, Sun, Wang, Li, Zhang, Zhao: "Disorganized vascular structures in sporadic venous malformations: a possible correlation with balancing effect between Tie2 and TGF-β." dans: Scientific reports, Vol. 4, pp. 5457, (2016) (PubMed).

  • Antigène
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Autre désignation
    TEK (TEK Produits)
    Synonymes
    anticorps TEK, anticorps DKFZp469E064, anticorps AA517024, anticorps Cd202b, anticorps Hyk, anticorps Tie2, anticorps tie-2, anticorps CD202B, anticorps TIE-2, anticorps TIE2, anticorps VMCM, anticorps VMCM1, anticorps Tie-2, anticorps tie2, anticorps TEK receptor tyrosine kinase, anticorps angiopoietin-1 receptor, anticorps TEK tyrosine kinase, endothelial, anticorps TEK, anticorps LOC100408334, anticorps tek, anticorps Tek
    Sujet
    This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.,TEK,CD202B,GLC3E,TIE-2,TIE2,VMCM,VMCM1,Tie2,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,Cardiovascular,Cardiovascular Markers,Endothelial Cells,Angiogenesis,TEK
    Poids moléculaire
    109 kDa/121 kDa/125 kDa
    ID gène
    7010
    UniProt
    Q02763
    Pathways
    Signalisation RTK, Growth Factor Binding
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