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C-JUN anticorps (pTyr170)

JUN Reactivité: Humain, Souris, Rat WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6255828
  • Antigène Voir toutes C-JUN (JUN) Anticorps
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    Épitope
    • 42
    • 42
    • 30
    • 29
    • 22
    • 16
    • 16
    • 15
    • 11
    • 11
    • 10
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr170
    Reactivité
    • 381
    • 208
    • 191
    • 34
    • 28
    • 21
    • 19
    • 17
    • 16
    • 12
    • 12
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 372
    • 17
    • 2
    Lapin
    Clonalité
    • 347
    • 44
    Polyclonal
    Conjugué
    • 191
    • 24
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 14
    • 14
    • 13
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp C-JUN est non-conjugé
    Application
    • 271
    • 136
    • 121
    • 89
    • 57
    • 46
    • 43
    • 43
    • 43
    • 23
    • 11
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Specificité
    Phospho-c-Jun (Tyr170) Antibody detects endogenous levels of c-Jun only when phosphorylated at Tyrosine 170.
    Homologie
    Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogène
    A synthesized peptide derived from human c-Jun around the phosphorylation site of Tyr170.
    Isotype
    IgG
    Top Product
    Discover our top product JUN Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:1000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    Autre désignation
    JUN (JUN Produits)
    Synonymes
    anticorps AP-1, anticorps AP1, anticorps c-Jun, anticorps fj36h07, anticorps wu:fj36h07, anticorps zgc:65863, anticorps Junc, anticorps c-jun, anticorps CG2275, anticorps D-Jun, anticorps D-jun, anticorps D-jun/Jra, anticorps DJUN, anticorps DJun, anticorps Djun, anticorps Dmel\\CG2275, anticorps JRA, anticorps JUN, anticorps Jun, anticorps V, anticorps cJun, anticorps d-JRA, anticorps d-Jun, anticorps d-jun, anticorps dAP-1, anticorps dJRA, anticorps dJUN, anticorps dJra, anticorps dJun, anticorps djun, anticorps dm-Jun, anticorps jra, anticorps jun, anticorps l(2)46Ef, anticorps l(2)IA109, anticorps l(2R)IA109, anticorps Jun proto-oncogene, AP-1 transcription factor subunit, anticorps jun proto-oncogene S homeolog, anticorps jun proto-oncogene, anticorps Jun-related antigen, anticorps jun proto-oncogene L homeolog, anticorps JUN, anticorps Jun, anticorps jun.S, anticorps jun, anticorps Jra, anticorps jun.L
    Sujet

    Description: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).

    Gene: JUN

    Poids moléculaire
    37kDa
    ID gène
    3725
    UniProt
    P05412
    Pathways
    Signalisation MAPK, Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
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