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PFKL anticorps (C-Term)

PFKL Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6257021
  • Antigène Voir toutes PFKL Anticorps
    PFKL (Phosphofructokinase, Liver (PFKL))
    Épitope
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 43
    • 24
    • 16
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 40
    • 5
    Lapin
    Clonalité
    • 41
    • 4
    Polyclonal
    Conjugué
    • 29
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PFKL est non-conjugé
    Application
    • 33
    • 17
    • 17
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    K6PL Antibody detects endogenous levels of total K6PL.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human K6PL, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product PFKL Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    PFKL (Phosphofructokinase, Liver (PFKL))
    Autre désignation
    PFKL (PFKL Produits)
    Synonymes
    anticorps PFK-B, anticorps AA407869, anticorps phosphofructokinase, liver type, anticorps phosphofructokinase, liver, B-type, anticorps PFKL, anticorps Pfkl
    Sujet

    Description: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (PubMed:22923583). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway (By similarity).

    Gene: PFKL

    Poids moléculaire
    85 kDa
    ID gène
    5211
    UniProt
    P17858
    Pathways
    Negative Regulation of Hormone Secretion, L'effet Warburg
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