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WTAP anticorps (C-Term)

WTAP Reactivité: Humain, Souris, Rat WB, ELISA, IHC, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6257553
  • Antigène Voir toutes WTAP Anticorps
    WTAP (Wilms Tumor 1 Associated Protein (WTAP))
    Épitope
    • 9
    • 8
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 50
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 43
    • 7
    Lapin
    Clonalité
    • 42
    • 8
    Polyclonal
    Conjugué
    • 29
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp WTAP est non-conjugé
    Application
    • 36
    • 27
    • 14
    • 8
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    WTAP Antibody detects endogenous levels of total WTAP.
    Homologie
    Horse,Sheep,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human WTAP, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product WTAP Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    WTAP (Wilms Tumor 1 Associated Protein (WTAP))
    Autre désignation
    WTAP (WTAP Produits)
    Synonymes
    anticorps MGC75954, anticorps WTAP, anticorps RGD1563824, anticorps wu:fi29a09, anticorps zgc:66202, anticorps 2810408K05Rik, anticorps 9430038B09Rik, anticorps WT1 associated protein, anticorps Wilms tumor 1 associated protein, anticorps wilms tumor 1 associated protein, anticorps WT1 associated protein L homeolog, anticorps Wilms tumour 1-associating protein, anticorps wtap, anticorps WTAP, anticorps CpipJ_CPIJ006489, anticorps Wtap, anticorps wtap.L
    Sujet

    Description: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator (PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724).

    Gene: WTAP

    Poids moléculaire
    44 kDa
    ID gène
    9589
    UniProt
    Q15007
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