CRHR2 anticorps (Internal Region)

N° du produit ABIN6257813

Détail du produit anti-CRHR2 anticorps

Antigène: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRHR2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: CRHR2 Antibody detects endogenous levels of total CRHR2.

Homologie: Pig,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CRHR2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CRHR2

Antigène: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Autre désignation: CRHR2 (CRHR2 Produits)

Synonymes: anticorps CRF-RB, anticorps CRF2, anticorps CRFR2, anticorps HM-CRF, anticorps CRF-R2, anticorps CRFR2alpha, anticorps CRFR2beta, anticorps Crfr2, anticorps Crf2r, anticorps CRH-R2, anticorps crhr2-A, anticorps corticotropin releasing hormone receptor 2, anticorps corticotropin releasing hormone receptor 2 S homeolog, anticorps CRHR2, anticorps Crhr2, anticorps crhr2.S

Sujet:

Description: G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.

Gene: CRHR2

Poids moléculaire: 48 kDa

ID gène: 1395

UniProt: Q13324

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Feeding Behaviour