BCOR anticorps (BCL6 Co-Repressor)

Details for Product anti-BCOR Antibody No. ABIN6257962
Antigène
  • ANOP2
  • MAA2
  • MCOPS2
  • BCOR
  • RGD1562735
  • 5830466J11Rik
  • 8430401K06Rik
  • BcorR
  • D930024N20Rik
  • mKIAA1575
  • BCL6 corepressor
  • BCL6 co-repressor
  • BCL6 interacting corepressor
  • BCOR
  • bcor
  • Bcor
Reactivité
Humain, Souris
72
38
9
3
3
3
1
1
1
1
1
Hôte
Lapin
53
15
7
Clonalité
Polyclonal
Conjugué
Cet anticorp BCOR est non-conjugé
4
2
2
2
2
2
2
2
2
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
39
38
19
5
5
5
4
3
2
1
Options
Immunogène A synthesized peptide
Isotype IgG
Specificité BCOR Antibody detects endogenous levels of total BCOR
 Réactivité croisée Humain, Souris
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Plasmids, Primers & others Plasmids, Primers & others BCOR products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation BCOR (BCOR Antibody Extrait)
Sujet

Description: Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A, impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells, the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).

Gene: BCOR

Poids moléculaire 192 kDa
ID gène 54880
UniProt Q6W2J9
Indications d'application WB 1:500~1:1000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at -20 °C.Stable for 12 months from date of receipt
Date de péremption 12 months
Images (Fournisseur)
Immunofluorescence (fixed cells) (IF/ICC) image for anti-BCL6 Co-Repressor (BCOR) antibody (ABIN6257962) ABIN6274592 staining COLO205 by IF/ICC. The sample were fixed with PFA and permeabili...
Immunohistochemistry (IHC) image for anti-BCL6 Co-Repressor (BCOR) antibody (ABIN6257962) ABIN6274592 at 1/100 staining Mouse colon tissue by IHC-P. The sample was formaldehyd...
Western Blotting (WB) image for anti-BCL6 Co-Repressor (BCOR) antibody (ABIN6257962) Western blot analysis of extracts from COLO cells, using BCOR antibody.
Western Blotting (WB) image for anti-BCL6 Co-Repressor (BCOR) antibody (ABIN6257962) Western blot analysis of extracts from Hela, using BCOR Antibody.
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