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CC2D1A anticorps (Internal Region)

CC2D1A Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6257986
  • Antigène Voir toutes CC2D1A Anticorps
    CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))
    Épitope
    • 8
    • 8
    • 7
    • 4
    • 3
    • 1
    Internal Region
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 33
    • 2
    Lapin
    Clonalité
    • 34
    • 1
    Polyclonal
    Conjugué
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CC2D1A est non-conjugé
    Application
    • 26
    • 15
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificité
    CC2D1A Antibody detects endogenous levels of total CC2D1A.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human CC2D1A, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CC2D1A Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Date de péremption
    12 months
  • Antigène
    CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))
    Autre désignation
    CC2D1A (CC2D1A Produits)
    Synonymes
    anticorps mrt3, anticorps freud-1, anticorps FREUD-1, anticorps Freud-1/Aki1, anticorps MRT3, anticorps BC016188, anticorps Freud-1, anticorps Tape, anticorps RGD1306108, anticorps coiled-coil and C2 domain containing 1A, anticorps CC2D1A, anticorps cc2d1a, anticorps Cc2d1a
    Sujet

    Description: Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses (By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.

    Gene: CC2D1A

    Poids moléculaire
    130 kDa
    ID gène
    54862
    UniProt
    Q6P1N0
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