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GPR52 anticorps (Internal Region)

GPR52 Reactivité: Humain, Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6258184
  • Antigène Voir toutes GPR52 Anticorps
    GPR52 (G Protein-Coupled Receptor 52 (GPR52))
    Épitope
    • 13
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 33
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 33
    Lapin
    Clonalité
    • 33
    Polyclonal
    Conjugué
    • 20
    • 3
    • 3
    • 3
    • 2
    • 2
    Cet anticorp GPR52 est non-conjugé
    Application
    • 23
    • 22
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificité
    GPR52 Antibody detects endogenous levels of total GPR52.
    Homologie
    Pig,Bovine,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human GPR52, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product GPR52 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Date de péremption
    12 months
  • Antigène
    GPR52 (G Protein-Coupled Receptor 52 (GPR52))
    Autre désignation
    GPR52 (GPR52 Produits)
    Synonymes
    anticorps GPR52, anticorps EG620246, anticorps G protein-coupled receptor 52, anticorps GPR52, anticorps Gpr52
    Sujet

    Description: Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241). May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241). Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228).

    Gene: GPR52

    Poids moléculaire
    41 kDa,
    ID gène
    9293
    UniProt
    Q9Y2T5
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