MARK1 anticorps
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- Antigène Voir toutes MARK1 Anticorps
- MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MARK1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- MARK Antibody detects endogenous levels of total MARK
- Réactivité croisée
- Humain, Souris, Rat (Rattus)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide
- Isotype
- IgG
- Top Product
- Discover our top product MARK1 Anticorps primaire
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- Indications d'application
- WB 1:500~1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
- Date de péremption
- 12 months
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- Antigène
- MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))
- Autre désignation
- MARK (MARK1 Produits)
- Synonymes
- anticorps MGC80341, anticorps MARK1, anticorps AW491150, anticorps B930025N23Rik, anticorps Emk3, anticorps Par-1c, anticorps mKIAA1477, anticorps mPar-1c, anticorps MARK, anticorps Par1c, anticorps MAP/microtubule affinity-regulating kinase 1 S homeolog, anticorps microtubule affinity regulating kinase 1, anticorps MAP/microtubule affinity-regulating kinase 1, anticorps MAP/microtubule affinity regulating kinase 1, anticorps mark1.S, anticorps MARK1, anticorps mark1, anticorps Mark1
- Sujet
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Description: Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).
Gene: MARK1
- Poids moléculaire
- 89 kDa
- ID gène
- 4139
- UniProt
- Q9P0L2, Q7KZI7, P27448, Q96L34
- Pathways
- SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2
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