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UBR1 anticorps (Internal Region)

UBR1 Reactivité: Humain, Souris WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6258376
  • Antigène Voir toutes UBR1 Anticorps
    UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))
    Épitope
    • 15
    • 14
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 40
    • 37
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 48
    • 4
    Lapin
    Clonalité
    • 49
    • 3
    Polyclonal
    Conjugué
    • 22
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp UBR1 est non-conjugé
    Application
    • 44
    • 30
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    UBR1 Antibody detects endogenous levels of total UBR1.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human UBR1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product UBR1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))
    Autre désignation
    UBR1 (UBR1 Produits)
    Synonymes
    anticorps Dmel\\CG9086, anticorps Ubr1, anticorps UBR1, anticorps JBS, anticorps AI504731, anticorps RGD1562326, anticorps Ubr1 ubiquitin ligase, anticorps ubiquitin protein ligase E3 component n-recognin 1, anticorps E3 ubiquitin-protein ligase ubr-1, anticorps Ubr1, anticorps ubr1, anticorps UBR1, anticorps ubr-1
    Sujet

    Description: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.

    Gene: UBR1

    Poids moléculaire
    36 kDa
    ID gène
    197131
    UniProt
    Q8IWV7
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