CENPT anticorps (Internal Region)

N° du produit ABIN6258439

Détail du produit anti-CENPT anticorps

Antigène: CENPT (Centromere Protein T (CENPT))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPT est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)

Specificité: CENPT Antibody detects endogenous levels of total CENPT.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CENPT, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur CENPT

Antigène: CENPT (Centromere Protein T (CENPT))

Autre désignation: CENPT (CENPT Produits)

Synonymes: anticorps cenp-t, anticorps MGC145722, anticorps CENP-T, anticorps wu:fc31h11, anticorps wu:fc75c05, anticorps C16orf56, anticorps G630055P03Rik, anticorps RGD1309383, anticorps centromere protein T, anticorps centromere protein T L homeolog, anticorps si:ch211-225g23.1, anticorps cenpt, anticorps cenpt.L, anticorps CENPT, anticorps si:ch211-225g23.1, anticorps Cenpt

Sujet:

Description: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPT has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis.

Gene: CENPT

Poids moléculaire: 65 kDa

ID gène: 80152

UniProt: Q96BT3