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ZC3H8 anticorps (Internal Region)

ZC3H8 Reactivité: Humain, Souris WB, ELISA, IHC, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6258445
  • Antigène Voir toutes ZC3H8 Anticorps
    ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))
    Épitope
    • 15
    • 8
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 37
    • 27
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 50
    • 2
    Lapin
    Clonalité
    • 50
    • 2
    Polyclonal
    Conjugué
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ZC3H8 est non-conjugé
    Application
    • 29
    • 19
    • 13
    • 13
    • 13
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    ZC3H8 Antibody detects endogenous levels of total ZC3H8.
    Homologie
    Pig,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human ZC3H8, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product ZC3H8 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))
    Autre désignation
    ZC3H8 (ZC3H8 Produits)
    Synonymes
    anticorps Zc3hdc8, anticorps DKFZp459D018, anticorps AU020882, anticorps E130108N08Rik, anticorps Fliz1, anticorps ZC3HDC8, anticorps zinc finger CCCH type containing 8, anticorps zinc finger CCCH-type containing 8, anticorps Zc3h8, anticorps ZC3H8
    Sujet

    Description: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

    Gene: ZC3H8

    Poids moléculaire
    40 kDa
    ID gène
    84524
    UniProt
    Q8N5P1
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