CCNB1IP1 anticorps (Internal Region)

N° du produit ABIN6258548

Détail du produit anti-CCNB1IP1 anticorps

Antigène: CCNB1IP1 (Cyclin B1 Interacting Protein 1 (CCNB1IP1))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCNB1IP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: CCNB1IP1 Antibody detects endogenous levels of total CCNB1IP1.

Homologie: Pig,Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CCNB1IP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CCNB1IP1

Antigène: CCNB1IP1 (Cyclin B1 Interacting Protein 1 (CCNB1IP1))

Autre désignation: CCNB1IP1 (CCNB1IP1 Produits)

Synonymes: anticorps Gm288, anticorps Hei10, anticorps mei4, anticorps C14orf18, anticorps HEI10, anticorps cyclin B1 interacting protein 1, anticorps CCNB1IP1, anticorps BDBG_07921, anticorps Ccnb1ip1

Sujet:

Description: Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL-gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.

Gene: CCNB1IP1

Poids moléculaire: 32 kDa

ID gène: 57820

UniProt: Q9NPC3