CD2AP anticorps (Internal Region)
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- Antigène Voir toutes CD2AP (Cd2ap) Anticorps
- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
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Épitope
- Internal Region
- Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CD2AP est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificité
- CD2AP Antibody detects endogenous levels of total CD2AP.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human CD2AP, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product Cd2ap Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
- Autre désignation
- CD2AP (Cd2ap Produits)
- Synonymes
- anticorps cd2apl, anticorps fj51c01, anticorps im:7153970, anticorps si:ch211-207n9.1, anticorps wu:fj51c01, anticorps zgc:103705, anticorps DKFZp469E061, anticorps CMS, anticorps AL024079, anticorps C78928, anticorps METS-1, anticorps Mets1, anticorps CD2-associated protein L homeolog, anticorps CD2 associated protein, anticorps CD2-associated protein, anticorps cd2ap.L, anticorps CD2AP, anticorps cd2ap, anticorps Cd2ap
- Sujet
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Description: Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton (PubMed:10339567). In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation (By similarity). May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell (By similarity). May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis (PubMed:15800069). Plays a role in epithelial cell junctions formation (PubMed:22891260).
Gene: CD2AP
- Poids moléculaire
- 74 kDa
- ID gène
- 23607
- UniProt
- Q9Y5K6
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