TP53BP2 anticorps (Internal Region)

N° du produit ABIN6258732

Détail du produit anti-TP53BP2 anticorps

Antigène: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TP53BP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: ASPP2 Antibody detects endogenous levels of total ASPP2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ASPP2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur TP53BP2

Antigène: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Autre désignation: TP53BP2 (TP53BP2 Produits)

Synonymes: anticorps 53BP2, anticorps ASPP2, anticorps BBP, anticorps P53BP2, anticorps PPP1R13A, anticorps TP53BP2, anticorps AI746547, anticorps Tp53bp2, anticorps X98550, anticorps Trp53bp2, anticorps wu:fa09h08, anticorps wu:fb04e08, anticorps zgc:85720, anticorps tumor protein p53 binding protein 2, anticorps tumor protein p53 binding protein 2 L homeolog, anticorps tumor protein p53 binding protein, 2b, anticorps transformation related protein 53 binding protein 2, anticorps tumor protein p53 binding protein, 2, anticorps tumor protein p53 binding protein, 2a, anticorps TP53BP2, anticorps tp53bp2.L, anticorps tp53bp2, anticorps tp53bp2b, anticorps Trp53bp2, anticorps Tp53bp2, anticorps tp53bp2a

Sujet:

Description: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Gene: TP53BP2

Poids moléculaire: 170 kDa

ID gène: 7159

UniProt: Q13625