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PARP2 anticorps (Internal Region)

PARP2 Reactivité: Humain, Souris WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259061
  • Antigène Voir toutes PARP2 Anticorps
    PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
    Épitope
    • 8
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 43
    • 37
    • 11
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Humain, Souris
    Hôte
    • 57
    • 1
    • 1
    Lapin
    Clonalité
    • 49
    • 10
    Polyclonal
    Conjugué
    • 27
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp PARP2 est non-conjugé
    Application
    • 36
    • 22
    • 7
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    PARP2 Antibody detects endogenous levels of total PARP2.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human PARP2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
    Autre désignation
    PARP2 (PARP2 Produits)
    Synonymes
    anticorps ADPRT2, anticorps ADPRTL2, anticorps ADPRTL3, anticorps ARTD2, anticorps PARP-2, anticorps pADPRT-2, anticorps Adprt2, anticorps Adprtl2, anticorps Aspartl2, anticorps C78626, anticorps cb996, anticorps adprtl2, anticorps ADPRT-2, anticorps APP, anticorps ATPARP1, anticorps PARP1, anticorps POLY(ADP-RIBOSE) POLYMERASE, anticorps POLY(ADP-RIBOSE) POLYMERASE 1, anticorps PP, anticorps T14P8.19, anticorps T14P8_19, anticorps poly(ADP-ribose) polymerase, anticorps poly(ADP-ribose) polymerase 2, anticorps poly(ADP-ribose) polymerase 2, anticorps poly (ADP-ribose) polymerase family, member 2, anticorps poly (ADP-ribose) polymerase 2, anticorps poly(ADP-ribose) polymerase 2 S homeolog, anticorps poly(ADP-ribose) polymerase, anticorps PARP2, anticorps Parp2, anticorps parp2, anticorps parp2.S
    Sujet

    Description: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism (PubMed:10364231, PubMed:28190768). This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (PubMed:10364231). Mediates serine ADP-ribosylation of target proteins following interaction with HPF1, HPF1 conferring serine specificity (PubMed:28190768).

    Gene: PARP2

    Poids moléculaire
    75 kDa
    ID gène
    10038
    UniProt
    Q9UGN5
    Pathways
    Réparation de l'ADN
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