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MASTL anticorps (C-Term)

MASTL Reactivité: Humain WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259100
  • Antigène Voir toutes MASTL Anticorps
    MASTL (Microtubule Associated serine/threonine Kinase-Like (MASTL))
    Épitope
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 46
    • 20
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 47
    • 14
    Lapin
    Clonalité
    • 46
    • 15
    Polyclonal
    Conjugué
    • 27
    • 7
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MASTL est non-conjugé
    Application
    • 47
    • 38
    • 8
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    MASTL Antibody detects endogenous levels of total MASTL.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human MASTL, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product MASTL Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    MASTL (Microtubule Associated serine/threonine Kinase-Like (MASTL))
    Autre désignation
    MASTL (MASTL Produits)
    Synonymes
    anticorps GW, anticorps GWL, anticorps MAST-L, anticorps im:7149025, anticorps wu:fa02a12, anticorps zgc:100990, anticorps MASTL, anticorps GREATWALL, anticorps RP11-85G18.2, anticorps THC2, anticorps hGWL, anticorps 2700091H24Rik, anticorps C88295, anticorps greatwall, anticorps thc2, anticorps microtubule associated serine/threonine kinase-like, anticorps microtubule associated serine/threonine kinase like, anticorps serine/threonine-protein kinase greatwall, anticorps microtubule associated serine/threonine kinase like L homeolog, anticorps mastl, anticorps MASTL, anticorps LOC100541707, anticorps Mastl, anticorps mastl.L
    Sujet

    Description: Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited. Phosphorylates histone protein in vitro, however such activity is unsure in vivo. May be involved in megakaryocyte differentiation.

    Gene: MASTL

    Poids moléculaire
    97 kDa
    ID gène
    84930
    UniProt
    Q96GX5
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