PARD3 anticorps (C-Term)
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- Antigène Voir toutes PARD3 Anticorps
- PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PARD3 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- PARD3 Antibody detects endogenous levels of total PARD3.
- Homologie
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human PARD3, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product PARD3 Anticorps primaire
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- Indications d'application
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))
- Autre désignation
- PARD3 (PARD3 Produits)
- Synonymes
- anticorps ASIP, anticorps Baz, anticorps PAR3, anticorps PAR3alpha, anticorps PARD-3, anticorps PARD3A, anticorps SE2-5L16, anticorps SE2-5LT1, anticorps SE2-5T2, anticorps Par3, anticorps AA960621, anticorps AI256638, anticorps D8Ertd580e, anticorps PAR-3, anticorps Pard3a, anticorps asip, anticorps bazooka, anticorps par-3, anticorps par3, anticorps pard3, anticorps par-3 family cell polarity regulator, anticorps partitioning defective 3 homolog, anticorps par-3 family cell polarity regulator alpha, b, anticorps par-3 family cell polarity regulator S homeolog, anticorps PARD3, anticorps Pard3, anticorps LOC100551156, anticorps LOC100473914, anticorps pard3, anticorps pard3ab, anticorps pard3.S
- Sujet
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Description: Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:27925688, PubMed:10954424). Seems to play a central role in the formation of epithelial tight junctions (PubMed:27925688). Targets the phosphatase PTEN to cell junctions (By similarity). Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly (By similarity). The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10934474). Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (PubMed:19812038, PubMed:27925688).
Gene: PARD3
- Poids moléculaire
- 151 kDa
- ID gène
- 56288
- UniProt
- Q8TEW0
- Pathways
- Cell-Cell Junction Organization
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