NFE2 anticorps (Internal Region)
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- Antigène Voir toutes NFE2 Anticorps
- NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NFE2 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- NFE2 Antibody detects endogenous levels of total NFE2.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human NFE2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product NFE2 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
- Autre désignation
- NFE2 (NFE2 Produits)
- Synonymes
- anticorps NF-E2, anticorps p45, anticorps 45kDa, anticorps p45NFE2, anticorps p45nf-e2, anticorps nuclear factor, erythroid 2, anticorps nuclear factor, erythroid derived 2, anticorps NFE2, anticorps Nfe2
- Sujet
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Description: Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Gene: NFE2
- Poids moléculaire
- 41 kDa
- ID gène
- 4778
- UniProt
- Q16621
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