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MIB2 anticorps (Internal Region)

MIB2 Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259538
  • Antigène Voir toutes MIB2 Anticorps
    MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))
    Épitope
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 20
    • 2
    Lapin
    Clonalité
    • 20
    • 2
    Polyclonal
    Conjugué
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MIB2 est non-conjugé
    Application
    • 10
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificité
    MIB2 Antibody detects endogenous levels of total MIB2.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human MIB2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product MIB2 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Date de péremption
    12 months
  • Antigène
    MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))
    Autre désignation
    MIB2 (MIB2 Produits)
    Synonymes
    anticorps ZZANK1, anticorps ZZZ5, anticorps 2210008I11Rik, anticorps Zzank1, anticorps skd, anticorps mib2, anticorps mindbomb E3 ubiquitin protein ligase 2, anticorps mindbomb E3 ubiquitin protein ligase 2 S homeolog, anticorps MIB2, anticorps Mib2, anticorps mib2, anticorps mib2.S
    Sujet

    Description: E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.

    Gene: MIB2

    Poids moléculaire
    ?110 kDa
    ID gène
    142678
    UniProt
    Q96AX9
    Pathways
    Signalisation Notch
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