ABCG8 anticorps (Internal Region)

N° du produit ABIN6259696

Détail du produit anti-ABCG8 anticorps

Antigène: ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCG8 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: ABCG8 Antibody detects endogenous levels of total ABCG8.

Homologie: Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ABCG8, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ABCG8

Antigène: ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))

Autre désignation: ABCG8 (ABCG8 Produits)

Synonymes: anticorps DDBDRAFT_0167690, anticorps DDBDRAFT_0191232, anticorps DDB_0167690, anticorps DDB_0191232, anticorps zgc:172358, anticorps GBD4, anticorps STSL, anticorps 1300003C16Rik, anticorps AI114946, anticorps sterolin-2, anticorps ATP binding cassette subfamily G member 8, anticorps ATP-binding cassette sub-family G member 8, anticorps ABC transporter G family protein, anticorps ATP-binding cassette, sub-family G (WHITE), member 8, anticorps ABCG8, anticorps PTRG_02054, anticorps abcG8, anticorps abcg8, anticorps Abcg8

Sujet:

Description: ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg2+- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:11099417, PubMed:11452359, PubMed:27144356, PubMed:15054092). Required for normal sterol homeostasis (PubMed:11099417, PubMed:11452359, PubMed:15054092). The heterodimer with ABCG5 has ATPase activity (PubMed:16893193, PubMed:20210363, PubMed:27144356).

Gene: ABCG8

Poids moléculaire: 76kDa

ID gène: 64241

UniProt: Q9H221

Pathways: Lipid Metabolism