AKAP10 anticorps (N-Term)

N° du produit ABIN6259849

Détail du produit anti-AKAP10 anticorps

Antigène: AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))

Épitope: N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP10 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: AKAP10 Antibody detects endogenous levels of total AKAP10.

Homologie: Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human AKAP10, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur AKAP10

Antigène: AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))

Autre désignation: AKAP10 (AKAP10 Produits)

Synonymes: anticorps MGC84612, anticorps AKAP10, anticorps fc10g11, anticorps wu:fc10g11, anticorps si:dkey-197m14.4, anticorps AKAP-10, anticorps D-AKAP-2, anticorps D-AKAP2, anticorps PRKA10, anticorps 1500031L16Rik, anticorps B130049N18Rik, anticorps D-akap2, anticorps Akap10, anticorps A-kinase anchoring protein 10, anticorps A-kinase anchoring protein 10 L homeolog, anticorps A kinase (PRKA) anchor protein 10, anticorps AKAP10, anticorps akap10.L, anticorps akap10, anticorps Akap10

Sujet:

Description: Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity).

Gene: AKAP10

Poids moléculaire: 73kDa

ID gène: 11216

UniProt: O43572

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling