TFAP2A anticorps (C-Term)

N° du produit ABIN6259960

Détail du produit anti-TFAP2A anticorps

Antigène: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFAP2A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Electrophoretic Mobility-Shift Assay (EMSA), Chromatin Immunoprecipitation (ChIP)

Specificité: AP2 alpha Antibody detects endogenous levels of total AP2 alpha.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human AP2 alpha, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, CHIP,EMSA, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TFAP2A

Antigène: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Autre désignation: TFAP2A (TFAP2A Produits)

Synonymes: anticorps TFAP2A, anticorps Ap-2, anticorps AP-2, anticorps AP-2alpha, anticorps AP2TF, anticorps BOFS, anticorps TFAP2, anticorps ap2, anticorps xap2, anticorps XAP-2, anticorps ap2tf, anticorps tfap2, anticorps ap-2alpha, anticorps tfap2alpha, anticorps cb93, anticorps fb83f04, anticorps fc31a07, anticorps wu:fb83f04, anticorps wu:fc31a07, anticorps tfap2a-a, anticorps tcfap2a, anticorps ap2a, anticorps AP2alpha, anticorps Ap2, anticorps Ap2tf, anticorps Tcfap2a, anticorps AP2, anticorps transcription factor AP-2 alpha, anticorps transcription factor AP-2, anticorps tto transcription factor AP-2 alpha, anticorps to transcription factor AP-2 alpha L homeolog, anticorps to transcription factor AP-2 alpha S homeolog, anticorps Transcription factor AP-2 alpha, anticorps transcription factor AP-2, alpha, anticorps TFAP2A, anticorps LOC100302602, anticorps tfap2a, anticorps tfap2a.L, anticorps tfap2a.S, anticorps ap2a, anticorps Tfap2a

Sujet:

Description: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.

Gene: TFAP2A

Poids moléculaire: 48 kDa

ID gène: 7020

UniProt: P05549

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Response to Water Deprivation, Sensory Perception of Sound, Tube Formation, Embryonic Body Morphogenesis, Brown Fat Cell Differentiation, Lipid Metabolism