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APOC3 anticorps (Internal Region)

APOC3 Reactivité: Humain, Rat, Souris WB, ELISA, IHC, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259991
  • Antigène Voir toutes APOC3 Anticorps
    APOC3 (Apolipoprotein C-III (APOC3))
    Épitope
    • 15
    • 11
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    Humain, Rat, Souris
    Hôte
    • 61
    • 11
    • 5
    Lapin
    Clonalité
    • 70
    • 7
    Polyclonal
    Conjugué
    • 33
    • 10
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp APOC3 est non-conjugé
    Application
    • 55
    • 32
    • 21
    • 14
    • 14
    • 11
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    APOC3 Antibody detects endogenous levels of total APOC3.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human APOC3, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product APOC3 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    APOC3 (Apolipoprotein C-III (APOC3))
    Autre désignation
    APOC3 (APOC3 Produits)
    Synonymes
    anticorps APOC3, anticorps APOCIII, anticorps HALP2, anticorps Apoc, anticorps ApoC-III, anticorps apo-CIII, anticorps Apo-CIII, anticorps apolipoprotein C3, anticorps apolipoprotein C-III, anticorps APOC3, anticorps Apoc3
    Sujet

    Description: Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma (PubMed:18201179, PubMed:22510806). Plays a multifaceted role in triglyceride homeostasis (PubMed:18201179, PubMed:22510806). Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion, extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs) (PubMed:18201179, PubMed:22510806). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors (PubMed:18201179, PubMed:22510806). Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners (PubMed:18408013).

    Gene: APOC3

    Poids moléculaire
    11 kDa
    ID gène
    345
    UniProt
    P02656
    Pathways
    Carbohydrate Homeostasis, Lipid Metabolism
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