ARF1 anticorps (Internal Region)
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- Antigène Voir toutes ARF1 Anticorps
- ARF1 (ADP-Ribosylation Factor 1 (ARF1))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ARF1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificité
- ARF1 Antibody detects endogenous levels of total ARF1.
- Homologie
- Pig,Zebrafish,Bovine,Sheep,Rabbit,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human ARF1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ARF1 Anticorps primaire
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- Indications d'application
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- ARF1 (ADP-Ribosylation Factor 1 (ARF1))
- Autre désignation
- ARF1 (ARF1 Produits)
- Synonymes
- anticorps wu:fb33e02, anticorps wu:fb78h01, anticorps arf2, anticorps arf-1, anticorps MGC52573, anticorps ADP-RIBOSYLATION FACTOR, anticorps ADP-RIBOSYLATION FACTOR 1A, anticorps ADP-ribosylation factor 1, anticorps ATARF, anticorps ATARF1, anticorps ATARFA1A, anticorps F28C11.12, anticorps ARF1, anticorps arf1, anticorps ADP ribosylation factor 1, anticorps ADP-ribosylation factor 1, anticorps ADP ribosylation factor 1 L homeolog, anticorps ADP ribosylation factor 5 L homeolog, anticorps ADP ribosylation factor 1 pseudogene, anticorps adp-ribosylation factor 1, anticorps ARF1, anticorps Arf1, anticorps arf1, anticorps arf1.L, anticorps arf5.L, anticorps NCU08340, anticorps TRIADDRAFT_63238, anticorps PAAG_08805, anticorps LOC100280562, anticorps LOC100280918, anticorps LOC474591, anticorps CLUG_01013
- Sujet
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Description: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity, the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD).
Gene: ARF1
- Poids moléculaire
- 20 kDa
- ID gène
- 375
- UniProt
- P84077
- Pathways
- Transition Metal Ion Homeostasis, Inositol Metabolic Process
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