ARHGEF7 anticorps (Internal Region)

N° du produit ABIN6260037

Détail du produit anti-ARHGEF7 anticorps

Antigène: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: ARHGEF7 Antibody detects endogenous levels of total ARHGEF7.

Homologie: Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ARHGEF7, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ARHGEF7

Antigène: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Autre désignation: ARHGEF7 (ARHGEF7 Produits)

Synonymes: anticorps BETA-PIX, anticorps COOL-1, anticorps COOL1, anticorps Nbla10314, anticorps P50, anticorps P50BP, anticorps P85, anticorps P85COOL1, anticorps P85SPR, anticorps PAK3, anticorps PIXB, anticorps cool1, anticorps p50, anticorps p85, anticorps pak3, anticorps pixb, anticorps ARHGEF7, anticorps P85spr, anticorps Pak3bp, anticorps Cool, anticorps PIX, anticorps betaPix, anticorps betaPix-b, anticorps betaPix-c, anticorps cool-1, anticorps mKIAA0142, anticorps p85Cool1, anticorps p85SPR, anticorps arhgef7, anticorps bbh, anticorps bpix, anticorps im:7142367, anticorps wu:fc35h08, anticorps zgc:101775, anticorps Rho guanine nucleotide exchange factor 7, anticorps Rho guanine nucleotide exchange factor 7 S homeolog, anticorps ankyrin repeat domain 10, anticorps Rho guanine nucleotide exchange factor (GEF7), anticorps Rho guanine nucleotide exchange factor (GEF) 7b, anticorps ARHGEF7, anticorps arhgef7.S, anticorps arhgef7, anticorps ANKRD10, anticorps Arhgef7, anticorps arhgef7b

Sujet:

Description: Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.

Gene: ARHGEF7

Poids moléculaire: 90kDa

ID gène: 8874

UniProt: Q14155

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation