ATG4B anticorps (Internal Region)

N° du produit ABIN6260105

Détail du produit anti-ATG4B anticorps

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG4B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: ATG4B Antibody detects endogenous levels of total ATG4B.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ATG4B, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ATG4B

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Autre désignation: ATG4B (ATG4B Produits)

Synonymes: anticorps apg4b, anticorps APG4B, anticorps AUTL1, anticorps 2510009N07Rik, anticorps AW048066, anticorps Apg4b, anticorps Atg4bl, anticorps Autl1, anticorps Aut2b2, anticorps autophagy related 4B cysteine peptidase, anticorps autophagy-related 4b, anticorps Peptidase family C54 protein, anticorps cysteine protease ATG4B, anticorps ATG4 autophagy related 4 homolog B (S. cerevisiae), anticorps autophagy related 4B, cysteine peptidase, anticorps autophagy related 4B, cysteine peptidase L homeolog, anticorps ATG4B, anticorps Atg4b, anticorps AT3G59950, anticorps Tsp_08582, anticorps Tsp_11599, anticorps atg4b, anticorps atg4b.L

Sujet:

Description: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Gene: ATG4B

Poids moléculaire: 44kDa

ID gène: 23192

UniProt: Q9Y4P1

Pathways: Autophagy