ARL6 anticorps (Internal Region)
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- Antigène Voir toutes ARL6 Anticorps
- ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ARL6 est non-conjugé
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Application
- Immunohistochemistry (IHC), Western Blotting (WB)
- Specificité
- BBS3 Antibody detects endogenous levels of total BBS3.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human BBS3, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ARL6 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))
- Autre désignation
- ARL6 (ARL6 Produits)
- Synonymes
- anticorps BBS3, anticorps RP55, anticorps 1110018H24Rik, anticorps 2210411E14Rik, anticorps zgc:101762, anticorps arl6, anticorps ADP ribosylation factor like GTPase 6, anticorps ADP-ribosylation factor-like 6, anticorps ADP-ribosylation factor like GTPase 6, anticorps ADP-ribosylation factor-like protein 6, anticorps ADP ribosylation factor like GTPase 6 L homeolog, anticorps ARL6, anticorps Arl6, anticorps arl6, anticorps arl-6, anticorps arl6.L
- Sujet
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Description: Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia (PubMed:20603001). Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia (By similarity). Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation (PubMed:22072986). May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade (PubMed:20207729). Isoform 2 may be required for proper retinal function and organization (By similarity).
Gene: ARL6
- Poids moléculaire
- 21 kDa
- ID gène
- 84100
- UniProt
- Q9H0F7
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