BCCIP anticorps (C-Term)

N° du produit ABIN6260217

Détail du produit anti-BCCIP anticorps

Antigène: BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCCIP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: BCCIP Antibody detects endogenous levels of total BCCIP.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human BCCIP, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur BCCIP

Antigène: BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

Autre désignation: BCCIP (BCCIP Produits)

Synonymes: anticorps zgc:110272, anticorps mp:zf637-1-000774, anticorps BCCIP, anticorps DKFZp459K2416, anticorps MGC82792, anticorps tok-1, anticorps MGC89311, anticorps TOK-1, anticorps TOK1, anticorps 1110013J05Rik, anticorps BRCA2 and CDKN1A interacting protein, anticorps BRCA2 and CDKN1A interacting protein L homeolog, anticorps BCCIP, anticorps bccip, anticorps bccip.L, anticorps Bccip

Sujet:

Description: During interphase, required for microtubule organizing and anchoring activities. During mitosis, required for the organization and stabilization of the spindle pole (PubMed:28394342). Isoform 2/alpha is particularly important for the regulation of microtubule anchoring, microtubule stability, spindle architecture and spindle orientation, compared to isoform 1/beta (PubMed:28394342). May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).

Gene: BCCIP

Poids moléculaire: 36 kDa

ID gène: 56647

UniProt: Q9P287