CIDEA anticorps

N° du produit ABIN6260840

Détail du produit anti-CIDEA anticorps

Antigène: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIDEA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: CIDEA Antibody detects endogenous levels of total CIDEA

Réactivité croisée: Humain

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CIDEA

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000 IHC 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur CIDEA

Antigène: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Autre désignation: CIDEA (CIDEA Produits)

Synonymes: anticorps CIDE-A, anticorps AW212747, anticorps CIDEA, anticorps cide-a, anticorps MGC89985, anticorps cell death-inducing DFFA-like effector a, anticorps cell death-inducing DNA fragmentation factor, alpha subunit-like effector A, anticorps cell death-inducing DFFA-like effector a L homeolog, anticorps CIDEA, anticorps Cidea, anticorps cidea, anticorps cidea.L

Sujet:

Description: Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter (By similarity). Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. When overexpressed, induces apoptosis. The physiological significance of its role in apoptosis is unclear.

Gene: CIDEA

Poids moléculaire: 25 kDa

ID gène: 1149

UniProt: O60543