CIDEC anticorps (Internal Region)

N° du produit ABIN6260841

Détail du produit anti-CIDEC anticorps

Antigène: CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIDEC est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: CIDEC Antibody detects endogenous levels of total CIDEC.

Homologie: Horse

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CIDEC, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CIDEC

Antigène: CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))

Autre désignation: CIDEC (CIDEC Produits)

Synonymes: anticorps fsp27, anticorps cide-3, anticorps MGC89274, anticorps cidec, anticorps MGC82483, anticorps CIDEC, anticorps fd36c01, anticorps wu:fd36c01, anticorps zgc:153033, anticorps CIDE-3, anticorps CIDE3, anticorps FPLD5, anticorps FSP27, anticorps Fsp27, anticorps CIDE-C, anticorps cell death inducing DFFA like effector c, anticorps cell death inducing DFFA like effector c S homeolog, anticorps cell death-inducing DFFA-like effector c, anticorps Cell death activator CIDE-3, anticorps cidec, anticorps cidec.S, anticorps CIDEC, anticorps Cidec

Sujet:

Description: Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression.

Gene: CIDEC

Poids moléculaire: 26 kDa

ID gène: 63924

UniProt: Q96AQ7