CISD2 anticorps (Internal Region)

N° du produit ABIN6260844

Détail du produit anti-CISD2 anticorps

Antigène: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CISD2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: CISD2 Antibody detects endogenous levels of total CISD2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CISD2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CISD2

Antigène: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Autre désignation: CISD2 (CISD2 Produits)

Synonymes: anticorps ERIS, anticorps Miner1, anticorps NAF-1, anticorps WFS2, anticorps ZCD2, anticorps 1500009M05Rik, anticorps 1500026J14Rik, anticorps 1500031D15Rik, anticorps AI848398, anticorps B630006A20Rik, anticorps Noxp70, anticorps Zcd2, anticorps RGD1566242, anticorps zgc:64148, anticorps eris, anticorps miner1, anticorps wfs2, anticorps zcd2, anticorps cisd2, anticorps BcDNA:RE49709, anticorps Dmel\\CG1458, anticorps CDGSH iron sulfur domain 2, anticorps CDGSH iron sulfur domain 2 L homeolog, anticorps CDGSH iron sulfur domain 2 S homeolog, anticorps CISD2, anticorps Cisd2, anticorps cisd2, anticorps cisd2.L, anticorps cisd2.S

Sujet:

Description: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca2+ stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.

Gene: CISD2

Poids moléculaire: 13-15 kDa

ID gène: 493856

UniProt: Q8N5K1

Pathways: Activation of Innate immune Response