CITED1 anticorps (Internal Region)

N° du produit ABIN6260846

Détail du produit anti-CITED1 anticorps

Antigène: CITED1 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CITED1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: CITED1 Antibody detects endogenous levels of total CITED1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CITED1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CITED1

Antigène: CITED1 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1))

Autre désignation: CITED1 (CITED1 Produits)

Synonymes: anticorps cited1, anticorps fi05d05, anticorps CITED1, anticorps MSG1, anticorps AI316840, anticorps AU019144, anticorps Msg1, anticorps Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1, anticorps Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1, anticorps similar to Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1), anticorps Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1, anticorps cited1, anticorps CITED1, anticorps Cited1

Sujet:

Description: Transcriptional coactivator of the p300/CBP-mediated transcription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling, stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.

Gene: CITED1

Poids moléculaire: 20 kDa

ID gène: 4435

UniProt: Q99966