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CLASP2 anticorps

CLASP2 Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6260858
  • Antigène Voir toutes CLASP2 Anticorps
    CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))
    Reactivité
    • 66
    • 17
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 64
    • 2
    • 2
    Lapin
    Clonalité
    • 64
    • 4
    Polyclonal
    Conjugué
    • 28
    • 7
    • 7
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CLASP2 est non-conjugé
    Application
    • 53
    • 37
    • 21
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificité
    CLASP2 Antibody detects endogenous levels of total CLASP2
     Réactivité croisée
    Humain
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human CLASP2
    Isotype
    IgG
    Top Product
    Discover our top product CLASP2 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C.Stable for 12 months from date of receipt
    Date de péremption
    12 months
  • Antigène
    CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))
    Autre désignation
    CLASP2 (CLASP2 Produits)
    Synonymes
    anticorps zgc:77279, anticorps DKFZp459M112, anticorps 1500004F14Rik, anticorps 8030404L10Rik, anticorps C77448, anticorps CLASP2beta, anticorps mKIAA0627, anticorps cytoplasmic linker associated protein 2, anticorps CLIP associating protein 2, anticorps clasp2, anticorps CLASP2, anticorps Clasp2
    Sujet

    Description: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.

    Gene: CLASP2

    Poids moléculaire
    141kDa
    ID gène
    23122
    UniProt
    O75122
    Pathways
    Dynamique des Microtubules, Maintenance of Protein Location
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