CREB1 anticorps (cAMP Responsive Element Binding Protein 1)

Details for Product anti-CREB1 Antibody No. ABIN6261023
Antigène
  • creb
  • CREB1
  • Creb1
  • CREB
  • 2310001E10Rik
  • 3526402H21Rik
  • AV083133
  • Creb
  • Creb-1
  • creb1
  • zgc:55598
  • cAMP responsive element binding protein 1
  • cAMP responsive element binding protein
  • cAMP responsive element binding protein 1 S homeolog
  • cAMP responsive element binding protein 1a
  • CREB1
  • creb1
  • CREB
  • Creb1
  • creb1.S
  • creb1a
Reactivité
Humain, Souris, Rat (Rattus)
599
381
342
45
37
34
34
27
23
22
16
14
14
6
6
6
2
1
1
1
1
Hôte
Lapin
534
72
7
1
Clonalité
Polyclonal
Conjugué
Cet anticorp CREB1 est non-conjugé
26
15
15
14
13
13
13
13
13
8
7
6
3
3
3
3
3
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
431
257
214
91
80
53
44
43
25
18
11
10
6
4
3
2
1
1
Options
Immunogène A synthesized peptide derived from human CREB
Isotype IgG
Specificité CREB Antibody detects endogenous levels of total CREB
 Réactivité croisée Humain, Souris, Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Plasmids, Primers & others Plasmids, Primers & others CREB1 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation CREB (CREB1 Antibody Extrait)
Sujet

Description: Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.

Gene: CREB1

Poids moléculaire 43kDa
ID gène 1385
UniProt P16220
Pathways Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
Indications d'application WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at -20 °C.Stable for 12 months from date of receipt
Date de péremption 12 months
Images (Fournisseur)
Image no. 1 for anti-cAMP Responsive Element Binding Protein 1 (CREB1) antibody (ABIN6261023) ABIN6269162 staining HeLa by IF/ICC. The sample were fixed with PFA and permeabilized...
Image no. 2 for anti-cAMP Responsive Element Binding Protein 1 (CREB1) antibody (ABIN6261023) ABIN6269162 at 1/100 staining Human breast cancer tissue by IHC-P. The sample was for...
Image no. 3 for anti-cAMP Responsive Element Binding Protein 1 (CREB1) antibody (ABIN6261023) Western blot analysis of CREB expression in UV treated HeLa whole cell lysates,The la...
Produit citée dans: Wang, Zhou, Guan, Yu, Wang: "β-Estradiol antagonizes the inhibitory effects of caffeine in BMMSCs via the ERβ-mediated cAMP-dependent PKA pathway." dans: Toxicology, Vol. 394, pp. 1-10, 2018 (PubMed).

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