CYP2C9 anticorps (Internal Region)

N° du produit ABIN6261198

Détail du produit anti-CYP2C9 anticorps

Antigène: CYP2C9 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP2C9 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Cytochrome P450 2C9 Antibody detects endogenous levels of total Cytochrome P450 2C9.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Cytochrome P450 2C9, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CYP2C9

Antigène: CYP2C9 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9))

Autre désignation: CYP2C9 (CYP2C9 Produits)

Synonymes: anticorps CPC9, anticorps CYP2C, anticorps CYP2C10, anticorps CYPIIC9, anticorps P450IIC9, anticorps cytochrome P450 family 2 subfamily C member 9, anticorps CYP2C9

Sujet:

Description: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics (PubMed:25994031). This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenytoin, tolbutamide and losartan (PubMed:25994031).

Gene: CYP2C9

Poids moléculaire: 56 kDa

ID gène: 1559

UniProt: P11712