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DDX5 anticorps (C-Term)

DDX5 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6261257
  • Antigène Voir toutes DDX5 Anticorps
    DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))
    Épitope
    • 19
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 69
    • 47
    • 40
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 61
    • 8
    • 1
    Lapin
    Clonalité
    • 52
    • 18
    Polyclonal
    Conjugué
    • 46
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DDX5 est non-conjugé
    Application
    • 55
    • 18
    • 16
    • 14
    • 14
    • 14
    • 11
    • 9
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    DDX5 Antibody detects endogenous levels of total DDX5.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human DDX5, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product DDX5 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))
    Autre désignation
    DDX5 (DDX5 Produits)
    Synonymes
    anticorps G17P1, anticorps HLR1, anticorps HUMP68, anticorps p68, anticorps 2600009A06Rik, anticorps Hlr1, anticorps wu:fa56a07, anticorps wu:fb11e01, anticorps wu:fb16c10, anticorps wu:fb53b05, anticorps ddx5, anticorps DEAD-box helicase 5, anticorps DEAD (Asp-Glu-Ala-Asp) box polypeptide 5, anticorps DEAD (Asp-Glu-Ala-Asp) box helicase 5, anticorps DEAD-box helicase 5 L homeolog, anticorps DDX5, anticorps Ddx5, anticorps ddx5, anticorps ddx5.L
    Sujet

    Description: Involved in the alternative regulation of pre-mRNA splicing, its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation, the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 transcriptional activity and involved in skeletal muscle differentiation. Transcriptional coactivator for p53/TP53 and involved in p53/TP53 transcriptional response to DNA damage and p53/TP53-dependent apoptosis. Transcriptional coactivator for RUNX2 and involved in regulation of osteoblast differentiation. Acts as transcriptional repressor in a promoter-specific manner, the function probably involves association with histone deacetylases, such as HDAC1. As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms.

    Gene: DDX5

    Poids moléculaire
    69kDa
    ID gène
    1655
    UniProt
    P17844
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus
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