DVL1 anticorps

N° du produit ABIN6261389

Détail du produit anti-DVL1 anticorps

Antigène: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DVL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: DVL1 Antibody detects endogenous levels of total DVL1

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human DVL1

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000 IHC 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur DVL1

Antigène: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Autre désignation: DVL1 (DVL1 Produits)

Synonymes: anticorps DVL, anticorps DVL1L1, anticorps DVL1P1, anticorps Dvl, anticorps mKIAA4029, anticorps dvl-1, anticorps DSH, anticorps DVL-1, anticorps dvl1, anticorps dvl2l, anticorps Xdsh, anticorps dsh1, anticorps dishevelled segment polarity protein 1, anticorps dishevelled, dsh homolog 1 (Drosophila), anticorps microRNA 6808, anticorps dishevelled segment polarity protein 1b, anticorps dishevelled segment polarity protein 1 L homeolog, anticorps DVL1, anticorps Dvl1, anticorps MIR6808, anticorps dvl1b, anticorps dvl1.L

Sujet:

Description: Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).

Gene: DVL1

Poids moléculaire: 75 kDa

ID gène: 1855

UniProt: O14640

Pathways: Signalisation WNT, Synaptic Membrane, Skeletal Muscle Fiber Development