E-cadherin anticorps (C-Term)

N° du produit ABIN6261408

Détail du produit anti-E-cadherin anticorps

Antigène: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp E-cadherin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: E-cadherin Antibody detects endogenous levels of total E-cadherin.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human E-cadherin, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Références pour anticorps anti-E-cadherin (ABIN6261408)

Yang, Zhou, Zhu, Fan, Liu, Duan, Tang, Shou, Zuo: "miR-200b-containing microvesicles attenuate experimental colitis associated intestinal fibrosis by inhibiting epithelial-mesenchymal transition." dans: Journal of gastroenterology and hepatology, Vol. 32, Issue 12, pp. 1966-1974, (2018) (PubMed).

Xu, Sun, Fang, Song, Yan, Chen, Jiang, Fei, Zhao, Leboeuf, Li, Wang, Janin, Wang, Zhao: "JAM-A overexpression is related to disease progression in diffuse large B-cell lymphoma and downregulated by lenalidomide." dans: Scientific reports, Vol. 7, Issue 1, pp. 7433, (2018) (PubMed).

Guo, Yan, Yan, Guo, Zhang, Zhang, Goltzman: "Tumor-associated macrophages induce the expression of FOXQ1 to promote epithelial-mesenchymal transition and metastasis in gastric cancer cells." dans: Oncology reports, Vol. 38, Issue 4, pp. 2003-2010, (2018) (PubMed).

Shi, Luo, Zhang, Wang, Zheng, Song, Wang, Zhang, Zhang, Li, Luo: "CRTC2 promotes non-small cell lung cancer A549 migration and invasion in vitro." dans: Thoracic cancer, Vol. 9, Issue 1, pp. 136-141, (2018) (PubMed).

Shao, Zhang, Ma, Lu, Meng, Li, Wang, Chen, Zhang, Han, Liu, Ma: "MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition." dans: Gene, Vol. 652, pp. 48-58, (2018) (PubMed).

Ran, Zhu, Deng, Zhang, Liu, Feng, Zhong, Lin, Tong, Su: "Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN." dans: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 54, (2018) (PubMed).

Huang, Song, Tao, Shao, Zeng, Xu, Qi, Sun: "Ovostatin 2 knockdown significantly inhibits the growth, migration, and tumorigenicity of cutaneous malignant melanoma cells." dans: PLoS ONE, Vol. 13, Issue 4, pp. e0195610, (2018) (PubMed).

Qi, Wang, Zhao, Cai, Tang, Wang: "Cinobufacini inhibits epithelial-mesenchymal transition of human hepatocellular carcinoma cells through c-Met/ERK signaling pathway." dans: Bioscience trends, Vol. 12, Issue 3, pp. 291-297, (2018) (PubMed).

Meng, Chen, Han, Qian, Wang, Zhong, Qin, Zhang, Gao, Lei, Yang, Yang, Zhang, Liu, Liu, Zhou, Sun, Yang: "Twist1 Regulates Vimentin through Cul2 Circular RNA to Promote EMT in Hepatocellular Carcinoma." dans: Cancer research, Vol. 78, Issue 15, pp. 4150-4162, (2018) (PubMed).

Li, Xiao, Yang, Qin, Gao, Liu, Zhou: "Parthenolide attenuated bleomycin-induced pulmonary fibrosis via the NF-κB/Snail signaling pathway." dans: Respiratory research, Vol. 19, Issue 1, pp. 111, (2018) (PubMed).

Wu, Chen, Xi, Wang, Sha, Luo, Zhu, Hong, Bu: "High glucose induces epithelial-mesenchymal transition and results in the migration and invasion of colorectal cancer cells." dans: Experimental and therapeutic medicine, Vol. 16, Issue 1, pp. 222-230, (2018) (PubMed).

Jin, Zhang, Zhao, Xu, Shao, Huang, Shi, Yang: "Responses of Intestinal Mucosal Barrier Functions of Rats to Simulated Weightlessness." dans: Frontiers in physiology, Vol. 9, pp. 729, (2018) (PubMed).

Jia, Xiao, Gongsun, Xin, Shang, Chen, Wang, Jiang: "CEP55 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma via the PI3K/Akt pathway." dans: OncoTargets and therapy, Vol. 11, pp. 4221-4232, (2018) (PubMed).

Zhang, Liu, Zhang, Cui, Li, Wang, Ren, Zhang: "FOXQ1 promotes gastric cancer metastasis through upregulation of Snail." dans: Oncology reports, Vol. 35, Issue 6, pp. 3607-13, (2017) (PubMed).

Bai, Wang, Han, Xie, Ji, Yin, Chen, Wang, Jiang, Qi, Jiang: "BCL2L10 inhibits growth and metastasis of hepatocellular carcinoma both in vitro and in vivo." dans: Molecular carcinogenesis, Vol. 56, Issue 3, pp. 1137-1149, (2017) (PubMed).

Wang, Wang, Ji, Zhu, Han: "Knockdown of Nucleostemin in an ovarian cancer SKOV-3 cell line and its effects on cell malignancy." dans: Biochemical and biophysical research communications, Vol. 487, Issue 2, pp. 262-267, (2017) (PubMed).

Li, Zhao, Huang, Wang, Zhu, Cao, Xiong, Deng: "MiR-93-5p promotes gastric cancer-cell progression via inactivation of the Hippo signaling pathway." dans: Gene, Vol. 641, pp. 240-247, (2017) (PubMed).

Xiang, Deng, Liu, Wan, Feng, Chen, Xiong: "MiR-1271 Inhibits Cell Proliferation, Invasion and EMT in Gastric Cancer by Targeting FOXQ1." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 36, Issue 4, pp. 1382-94, (2016) (PubMed).

Li, Zhang, Sun, Sun, Shi, Liu, Liu: "MicroRNA-181a regulates epithelial-mesenchymal transition by targeting PTEN in drug-resistant lung adenocarcinoma cells." dans: International journal of oncology, Vol. 47, Issue 4, pp. 1379-92, (2016) (PubMed).

Détails sur E-cadherin

Antigène: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Autre désignation: CDH1 (CDH1 Produits)

Synonymes: anticorps Arc-1, anticorps CD324, anticorps CDHE, anticorps ECAD, anticorps LCAM, anticorps UVO, anticorps E-cadherin, anticorps cdh1, anticorps si:dz180o5.2, anticorps uvo, anticorps lcam, anticorps E-Cad, anticorps XBcad, anticorps l-cam, anticorps xcdh1, anticorps cdhc-A, anticorps xb-cad, anticorps XTCAD-1, anticorps c-cadherin, anticorps cadherin-1, anticorps uvomorulin, anticorps XB-cadherin, anticorps arc-1, anticorps cd324, anticorps cdhe, anticorps ecad, anticorps AA960649, anticorps E-cad, anticorps Ecad, anticorps L-CAM, anticorps Um, anticorps cadherin 1, anticorps si:busm1-180o5.2, anticorps cadherin 1, type 1, E-cadherin (epithelial), anticorps cadherin 1, type 1 S homeolog, anticorps CDH1, anticorps si:busm1-180o5.2, anticorps cdh1, anticorps Cdh1, anticorps cdh1.S

Sujet:

Description: Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.

Gene: CDH1

Poids moléculaire: 120kDa

ID gène: 999

UniProt: P12830

Pathways: Signalisation WNT, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation