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ESR2 anticorps

ESR2 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6261611
  • Antigène Voir toutes ESR2 Anticorps
    ESR2 (Estrogen Receptor 2 (ESR2))
    Reactivité
    • 191
    • 113
    • 94
    • 32
    • 19
    • 16
    • 15
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    Humain, Souris, Rat
    Hôte
    • 168
    • 36
    • 1
    • 1
    Lapin
    Clonalité
    • 161
    • 45
    Polyclonal
    Conjugué
    • 94
    • 18
    • 15
    • 9
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ESR2 est non-conjugé
    Application
    • 172
    • 76
    • 55
    • 39
    • 38
    • 26
    • 26
    • 19
    • 11
    • 11
    • 10
    • 10
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Estrogen Receptor-beta Antibody detects endogenous levels of total Estrogen Receptor-beta
     Réactivité croisée
    Humain, Souris, Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human Estrogen Receptor-beta
    Isotype
    IgG
    Top Product
    Discover our top product ESR2 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C.Stable for 12 months from date of receipt
    Date de péremption
    12 months
  • Antigène
    ESR2 (Estrogen Receptor 2 (ESR2))
    Autre désignation
    Estrogen Receptor-beta (ESR2 Produits)
    Synonymes
    anticorps ER-BETA, anticorps ESR-BETA, anticorps ESRB, anticorps ESTRB, anticorps Erb, anticorps NR3A2, anticorps ER[b]1, anticorps zfER-beta1, anticorps zfER[b]1, anticorps erb2, anticorps CERB, anticorps ERB, anticorps erb, anticorps esrb, anticorps estrb, anticorps nr3a2, anticorps ERbeta, anticorps er-beta, anticorps esr-beta, anticorps ESR2, anticorps ERBETA, anticorps er, anticorps ER-beta, anticorps ER[b], anticorps Estrb, anticorps ER[b]2, anticorps ER[b]a, anticorps zfER[b]2, anticorps zfER-beta2, anticorps Erb2, anticorps esr2, anticorps erbeta, anticorps Esr2, anticorps ERBeta2, anticorps estrogen receptor 2, anticorps estrogen receptor 2b, anticorps estrogen receptor beta 2, anticorps estrogen receptor 2 (beta), anticorps estrogen receptor 2a, anticorps estrogen receptor beta, anticorps ESR2, anticorps esr2b, anticorps erb2, anticorps esr2, anticorps Esr2, anticorps esr2a, anticorps erbeta
    Sujet

    Description: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner (PubMed:20074560). Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.

    Gene: ESR2

    Poids moléculaire
    59kDa
    ID gène
    2100
    UniProt
    Q92731
    Pathways
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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